Teatro Regio di Torino, La Fenice di Venezia, Amsterdam Concertgebouw, Cuvilliès in Munchen, Opéra de Lyon, Seoul Opera, Opéra de Montecarlo, Narodni Divadlo in Prague, Comunale di Bologna, Verdi di Firenze, Comunale di Firenze, Grand Theâtre in Geneve, Comunale di Modena, Seattle Theatre, Opéra de Montpellier, Madrid Auditorio, Opera di Roma…

He has appeared with many internationally recognized orchestras, such as the Orchestra del Teatro alla Scala, Radio France, Freiburger Orchester, Mozarteum Orchester, Accademia di Santa Cecilia, Orchestre Revolutionnaire et Romantique, Accademia Bizantina, L’Europa galante, Les Arts Florissants, La Venexiana, Orchestra della Toscana, Orchestra del Maggio Fiorentino, I Pomeriggi musicali, Orchestra della Valle d’Itria, La Verdi di Milano.

He debut in the baroque repertoire in 1991 with M. A. Charpentier’s Te Deum. Since then, there have been countless concerts and works performed including over 50 performances of Messiah by G.F. Händel, the Mass in B minor and numerous cantatas by J.S. Bach, rediscovery and execution of world premieres of madrigals by Giulio Cesare Monteverdi, works by B. Marini, B. Marcello and other authors of the Baroque Renaissance period.

In 2005, he made his debut at the Teatro alla Scala in the baroque repertoire as Rinaldo by Haendel conducted by Ottavio Dantone. Again in 2011, 2015 and 2016 he has been singing in Scala in Il ritorno di Ulisse in patria and L’Incoronazione di Poppea by Monteverdi under the baton of Rinaldo Alessandrini.

In 2008, he has been the recipient of a Grammy Award, Choc du Monde and Amadeus Prize thanks to a version of Monteverdi’s Orfeo together with La Venexiana and Claudio Cavina, nominated best baroque opera cd of the year. Together with great maestros such as J. E. Gardiner, W. Christie, I. Bolton, R. Alessandrini, R. Jacobs, P. Neumann, O. Dantone, F. Biondi, F. Bernius, G. Antonini, E. Onofri e C. Cavina he has been studying the baroque repertoire in depth.

He deepens the immense baroque repertoire with great masters such as John Eliot Gardiner, William Christie, Ivor Bolton, Rinaldo Alessandrini, Réné Jacobs, Ottavio Dantone, Fabio Biondi, A. De Marchi, Frieder Bernius, Giovanni Antonini, Enrico Onofri, Claudio Cavina, Peter Neumann.

Guadagnini also boasts a profound knowledge of lieder repertoire. In fact, in 2007 he founded the Festival Liederìadi, the only Lieder festival in Italy, which has hosted the best interpreters of this repertoire at international level and in which almost all the most and least known Lieder cycles from the Romantic period to the 20th century have been performed.

He has also a profound knowledge of modern and contemporary works and authors. Among other works interpreted, in 2014 is the turn of B. Britten’s War Requiem with the Orchestra Verdi in Milan under the baton of conductor Zhang Xian and again in 2018 in South Korea.

Below a list of the composers and relevant performances, in chronological order:
Azio Corghi (Il dissoluto assolto, Teatro alla Scala, Lisbon theatre 2006).
Federico Gardella (Nachtmusik, Milano 2006)
Ivan Fedele (Antigone, Maggio Fiorentino, Premio Abbiati 2007),
Hans Werner Henze (Phaedra, Maggio Fiorentino, Premio Abbiati 2008),
Matteo D’Amico (Patto di sangue, Maggio Fiorentino 2009),
Filippo del Corno (Non guardate al domani, Milano 2008),
Claudio Ambrosini (Killer di parole, Fenice di Venezia 2010)
Brian Current (Airlines Icarus, Verbania 2011)
Filippo Del corno (Le remède de fortune, Teatro Strehler, Milano 2012)
Karl Heinz Stockhausen (Stimmung, Los Angeles, Bologna Festival 2014)
Mauro Montalbetti (Corpi eretici -Teatro Valli, Reggio Emilia 2015)
Carlo Galante (Il bacio della Lady – Teatro Pavarotti, Modena 2015)
Fabio Vacchi (Lo specchio magico – Opera di Firenze, 2016)
Filippo Perocco (Aquagranda – Teatro alla Fenice, Premio Abbiati 2016)
Mauro Montalbetti – Still Requies (Teatro dell’Arte, Milano – Festival Internazionale di Musica Sacra, Pordenone – Teatro Grande, Brescia 2018)
Ivan Fedele – Thanatoséros (Auditorium Parco della Musica, Roma, 2019

He debuts as conductor in 2013 with the Petite Messe by Rossini. Since, he has intensified his conducting activity, giving a number of concerts both at Festival Liederiadi (Chabrier, Debussy, A. Ramirez, Stabat Mater by Pergolesi, Via Crucis by Liszt) and in other venues in Milano.
In 2015, he has also conducted an opera transposition of Romancero Gitano by Castelnuovo-Tedesco, named Volver, and in March 2016 the opera Amadigi di Gaula by Handel at Piccolo Teatro Studio in Milano, then the Stabat Mater by Rossini (2018) and Requiem K626 by Mozart (2018). In 2019 he conducted the Chichester Psalms by L. Bernstein.

He is a permanent member of the Baroque Ensemble Il Pegaso.
He is founder and director of Intende Voci.
He is president and founder of the Associazione Liederìadi with which he has been organizing for 15 years the Festival Liederìadi in Milan, the first and only lieder festival in Italy, of which he is artistic director.
He is founder and artistic director of the Festival “Musica in Abbazia” at the Abbey of Morimondo (Mi), which opened in May 2018.
He is the creator of the project “Auditorium in Musica”, a training-listening course on repertoires ranging from baroque to contemporary at the Auditorium Stefano Cerri in Milan.

He is Professor of Canto Rinascimentale e Barocco in A.Vivaldi’s Conservatory in Alessandria.